501 on First is Rochester’s premier luxury apartment is located in the heart of the city, just a few blocks away from the Mayo Clinic. Residents will have spectacular views of the growing downtown. 501 on First is the perfect location for providing residents access to all the retail, dining, and entertainment options that downtown Rochester, MN has to offer. Stay active with our 24 hour fitness center or choose one of the nearby walking trails. Sophisticated and ultra-luxurious, 501 on First represents a new level of vibrant city living.